Articles & Supplements
Articles & Supplements
- Review Article
- DOI: 10.5935/2526-8732.20220352
- 5 Views
- 1 citation
- Published in
Spirituality in oncology - a consensus by the Brazilian Society of Clinical Oncology
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ABSTRACT Spirituality is a dynamic and an intrinsic aspect of humanity and is usually intense in cancer for patients, families, and health care teams. Evidence on spirituality, health, and healing have increased over the last decades. This consensus is for those involved in cancer patient care, with concepts and possible...
- Review Article
- DOI: 10.5935/2526-8732.20240446
- 5 Views
- 0 citations
- Published in
Preventive and therapeutic assessment program for mucositis in patients with cancer: promising advances in stomatological care
, , , , , , , , , , , , , , , , , ,
ABSTRACT Objectives: We propose a preventive and therapeutic assessment program for mucositis in patients with cancer based on a comprehensive review of scientific evidence. Material and Methods: This methodological study, designed as a non-systematic review, entails a thorough review of the scientific evidence on the management of mucositis in patients...
- Original Article, Original Articles
- DOI: 10.1055/s-0046-1822975
- 5 Views
- 0 citations
- Published in
Impact of Sociodemographic Factors on the Time to Initiate Breast Cancer Treatment at a High-Complexity Hospital in Porto Alegre, Brazil
Abstract Introduction Time between cancer diagnosis and the start of treatment is crucial for patient prognosis. In the Brazilian public health system, this interval varies significantly. Access to timely care is shaped by multiple interconnected factors, including service organization, diagnostic processes, and follow-up care. Social aspects, such as ethnicity, level...
- Original Article, Original Articles
- DOI: 10.5935/2526-8732.20220339
- 5 Views
- 0 citations
- Published in
Analysis of trastuzumab therapy's efficacy with or without pertuzumab combination in the metastatic HER2-positive breast cancer an oncology hospital of Pernambuco
ABSTRACT Objectives: To evaluate the efficacy between trastuzumab-only or pertuzumab plus trastuzumab therapies in metastatic HER2-positive breast cancer patients. Material and Methods: At Hospital de Cancer de Pernambuco (HCP), Recife, Brazil, a cross-sectional study was carried out. One hundred seventy-two patients with HER2-positive metastatic breast cancer (BC) were divided into two groups....
- Original Article, Original Articles
- DOI: 10.5935/2526-8732.20200297
- 4 Views
- 0 citations
- Published in
Clinical and sociodemographic profile of patients with cutaneous melanoma attended at an oncology referral hospital in Florianópolis between 2013 and 2017
ABSTRACT Introduction: Cutaneous melanoma is the most lethal skin cancer and its incidence has significantly increased in recent years. In particular, Florianópolis is the Brazilian capital with the highest incidence of the disease. Objective: To investigate the clinical and sociodemographic profile of patients with cutaneous melanoma treated at a public oncology referral...
- Original Article, Original Articles
- DOI: 10.5935/2526-8732.20200293
- 4 Views
- 0 citations
- Published in
Quality of life of caregivers of patients with gastrointestinal cancer: relationship of sex, age, and stage of the cancer patients
ABSTRACT Introduction: The caregivers of cancer patients may experience changes in their routine that affect their quality of life. The aim of the study was to identify the domains that compromise the quality of life (QoL) of the caregivers of patients with gastrointestinal cancer (GIC). Methods: A descriptive, observational study with caregivers...
- Case Report
- DOI: 10.1055/s-0045-1811529
- 4 Views
- 0 citations
- Published in
Infrared Thermography – A Novel Tool in the Surgical Treatment of H3 K27M-Altered Diffuse Midline Spinal Cord Glioma: Technical and Case Report
Abstract Diffuse midline gliomas (DMGs), H3K27-altered, are rare and aggressive tumors primarily affecting children, though adult cases occur. These gliomas present significant surgical challenges, and novel techniques are needed to improve outcomes. We present the case of a 53-year-old male with a solid expansive lesion located at T12 to L1,...
- Review Article
- DOI: 10.5935/2526-8732.20240468
- 4 Views
- 0 citations
- Published in
Gastrointestinal stromal tumors: advances in molecular characterization and therapeutic implications
, , , , , , , , , , ,
ABSTRACT Recognition of the molecular basis of gastrointestinal stromal tumors has paved the way for significant breakthroughs in the diagnosis and treatment of this disease as well as positioned gastrointestinal stromal tumors as a framework for the concept of precision oncology in solid tumors. The incorporation of novel targeted agents...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1814367
- 4 Views
- 0 citations
- Published in
Dexamethasone and Diphenhydramine Withdrawal and Quality of Life Assessment in Breast Cancer Patients Receiving Weekly Paclitaxel
Abstract Introduction Maintenance of quality of life (QoL) is an important endpoint in cancer patients. Several studies have demonstrated that chemotherapy in breast cancer patients is related to worsening QoL scores. Taxanes are widely used in breast cancer treatment, and premedication omission in weekly paclitaxel has been evaluated in clinical...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1814171
- 4 Views
- 0 citations
- Published in
Time until Oncologic Treatment Approval in Brazil Compared to Europe and the United States
Abstract Introduction Oncology therapy development has accelerated worldwide, with approvals based on safety and efficacy. This study compares approval timelines in Brazil, the United States, and Europe from 2010 to 2021, highlighting regulatory differences and their impact on patient access. In Brazil, after Brazilian Health Regulatory Agency (Agência Nacional de...
- Case Report
- DOI: 10.1055/s-0045-1810445
- 3 Views
- 0 citations
- Published in
Papillary Carcinoma in a Thyroglossal Cyst: A Case Report
Abstract We herein report a case of papillary thyroid carcinoma with an unusual presentation, inside a thyroglossal cyst. An 83-year-old male patient reported a long-standing nodule persisting for over 40 years, with progressive enlargement and periodic dysphonia. The patient underwent total thyroidectomy combined with the Sistrunk procedure. Resection of the...
- Letter to the Editor
- DOI: 10.1055/s-0045-1809889
- 3 Views
- 0 citations
- Published in
Pharmacogenetic Testing for Fluoropyrimidines at Instituto Nacional de Câncer, Brazil
The present letter focuses on the pharmacogenetic (PGx) testing of variants of the dihydropyrimidine dehydrogenase (DPYD) gene available at Instituto Nacional de Câncer (INCA), Rio de Janeiro, for cancer patients who are candidates for treatment with the fluoropyrimidines 5-fluorouracil (5-FU) and/or capecitabine.1 The rationale for DPYD genotyping is as follows:...
- Review Article
- DOI: 10.5935/2526-8732.20220300
- 3 Views
- 1 citation
- Published in
Safe prescription of systemic antineoplastic treatment in oncology: integrative literature review
ABSTRACT The objective of this study was to identify the available evidence on the parameters that should be considered to improve the quality and safety of the prescription of systemic antineoplastic treatment. This is an integrative review carried out in the EMBASE, LILACS, and PubMed databases, from 2015 to 2019....
- Case Report
- DOI: 10.5935/2526-8732.20220343
- 3 Views
- 0 citations
- Published in
Incidental finding of sex cord tumor with annular tubules in ovary associated with Peutz-Jeghers syndrome
ABSTRACT Sex cord tumor with annular tubules (SCTAT) is a rare ovarian pathology. It is usually an incidental finding in asymptomatic patients. In about 30% of cases, this tumor is associated with the Peutz-Jeghers syndrome (PJS). This case report describes an incidental finding of SCTAT during an excisional surgery of...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1809931
- 3 Views
- 0 citations
- Published in
Analysis of the Impact of the SARS-CoV-2 Pandemic on the Stage and Access to Oncology Services in Brazil for the Treatment of Rectal Cancer
Abstract Introduction Cancer is a major social, public health, and economic challenge worldwide, accounting for 1 in 6 deaths globally, according to Globocan 2022. Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there has been a noticeable impact on the provision of services to oncology patients. The present...
- Original Article, Original Articles
- DOI: 10.1055/s-0046-1822975
- 5 Views
- 0 citations
- Published in
Impact of Sociodemographic Factors on the Time to Initiate Breast Cancer Treatment at a High-Complexity Hospital in Porto Alegre, Brazil
Abstract Introduction Time between cancer diagnosis and the start of treatment is crucial for patient prognosis. In the Brazilian public health system, this interval varies significantly. Access to timely care is shaped by multiple interconnected factors, including service organization, diagnostic processes, and follow-up care. Social aspects, such as ethnicity, level...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1814367
- 4 Views
- 0 citations
- Published in
Dexamethasone and Diphenhydramine Withdrawal and Quality of Life Assessment in Breast Cancer Patients Receiving Weekly Paclitaxel
Abstract Introduction Maintenance of quality of life (QoL) is an important endpoint in cancer patients. Several studies have demonstrated that chemotherapy in breast cancer patients is related to worsening QoL scores. Taxanes are widely used in breast cancer treatment, and premedication omission in weekly paclitaxel has been evaluated in clinical...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1814171
- 4 Views
- 0 citations
- Published in
Time until Oncologic Treatment Approval in Brazil Compared to Europe and the United States
Abstract Introduction Oncology therapy development has accelerated worldwide, with approvals based on safety and efficacy. This study compares approval timelines in Brazil, the United States, and Europe from 2010 to 2021, highlighting regulatory differences and their impact on patient access. In Brazil, after Brazilian Health Regulatory Agency (Agência Nacional de...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1814172
- 3 Views
- 0 citations
- Published in
Temporal and Spatial Analysis of Lung Cancer Mortality in a Northeastern Brazilian State from 1980 to 2022
Abstract Introduction Lung cancer is the most lethal cancer in the world. In Brazil, it is the third most common in men and the fourth in women. In Sergipe, this disease was the leading cause of cancer deaths from 2014 to 2018. Objectives To evaluate the mortality trend due to...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1814175
- 3 Views
- 0 citations
- Published in
Preconsultation Anxiety and Pain during Blood Collection: Impact of Virtual Reality in Children with Cancer – Randomized Clinical Trial
Abstract Introduction Virtual reality (VR) has expanded into diverse healthcare contexts, including pediatric oncology, in which it serves as a non-pharmacological tool for pain and anxiety relief. Objective To analyze the effect of VR glasses on pain and anxiety before a medical consultation during initial blood collection in pediatric oncology...
- Original Article, Original Articles
- DOI: 10.1055/s-0046-1817024
- 2 Views
- 0 citations
- Published in
Understanding Barriers to Clinical Trial Participation Among Cancer Patients: Insights from a Brazilian Oncology Center
Abstract Introduction Clinical trials are essential for advancing cancer care, yet patient participation remains low, particularly in regions with limited awareness such as Brazil. Materials and Methods This cross-sectional survey was conducted between 2020 and 2022 at a single cancer center in São Paulo, Brazil. Adult cancer patients completed a...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1815742
- 2 Views
- 0 citations
- Published in
Crowdsourcing Molecular Knowledge: A Practical and Affordable Approach to Create a Molecular Tumor Board
Abstract Objective To evaluate the feasibility and effectiveness of implementing virtual molecular tumor boards (MTBs) through crowdsourcing molecular knowledge among Brazilian physicians to comprehensively discuss complex genomic information on cancer patients. Materials and Methods We established a virtual group on WhatsApp (Meta Platforms, Inc.) consisting of medical oncologists, radiation therapists,...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1815743
- 3 Views
- 0 citations
- Published in
Multidimensional Assessment of the Impact of Li-Fraumeni Syndrome on Patients in Educational and Pedagogical Settings: From Molecular to Psychosocial Aspects*
Abstract Introduction Li-Fraumeni syndrome (LFS) is a rare hereditary cancer predisposition syndrome caused by mutations in the TP53 gene. It presents a clinical challenge due to its wide phenotypic variability and significant psychosocial implications for affected individuals and their families. Objective To improve the identification, management, and follow-up strategies for...
- Original Article, Original Articles
- DOI: 10.1055/s-0046-1817026
- 3 Views
- 0 citations
- Published in
Radionuclide Therapy for Bone Pain in Cancer Patients in Brazil (2015–2023): A Comparative Analysis of Public and Private Health Systems in the Context of the COVID-19 Pandemic
Abstract Introduction Bone metastases are common in advanced cancer and often result in severe pain. Radionuclide therapy with Beta-emitting radiopharmaceuticals, such as samarium-153 and strontium-89, is a recognized option for palliative management. The coronavirus disease 2019 (COVID-19) pandemic disrupted oncology care worldwide, including access to nuclear medicine services in Brazil....
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1811729
- 2 Views
- 0 citations
- Published in
Association between Spirituality, Religiosity, and Breast Cancer Treatment
Abstract To assess the degree of spirituality and religiosity in patients with breast cancer and its relationship with treatment, the Spiritual/Religious Coping (SRCOPE) scale and World Health Organization's Quality of Life Instrument – Spirituality, Religion and Personal Beliefs Module (WHOQOL-SRPB) questionnaires were applied to 49 patients. For 91.9% of the...
- Case Report
- DOI: 10.1055/s-0045-1812027
- 0 Views
- 0 citations
- Published in
Case Report: Spondylodiscitis as a Differential Diagnosis of Anal Canal Squamous Cell Carcinoma Bone Metastasis
Abstract Spondylodiscitis is an uncommon infection affecting the vertebral bodies and surrounding tissues, with an increased incidence in immunosuppressed patients. Back pain is the most common symptom, and early imaging often fails to reveal specific findings. Squamous cell carcinoma (SCC) of the anal canal accounts for 80% of the cases...
- Case Report
- DOI: 10.1055/s-0045-1812295
- 3 Views
- 0 citations
- Published in
The Potential of Hypofractionated Radiotherapy: A Revolutionary Treatment for Anorectal Malignant Melanomas
Abstract Mucosal melanomas generally arise from mucosal epithelium lining the respiratory, alimentary, and genitourinary tracts and usually carry worse prognosis than cutaneous melanomas. Anorectal melanomas account for 50% of gastrointestinal tract melanomas and 0.3 to 1% of all malignant melanomas. There are no specific treatment guidelines due to the scarcity...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1811732
- 3 Views
- 0 citations
- Published in
Prevalence and Management of Immediate Adverse Reactions to Chemotherapy in Breast Cancer Patients: A Retrospective Study
Abstract Objective To analyze the prevalence, characteristics, and management of immediate adverse reactions (ARs) to chemotherapeutic agents in breast cancer patients treated at the National Cancer Institute (Instituto Nacional del Cáncer, INCAN, in Spanish) in Paraguay. Materials and Methods A retrospective, observational, and cross-sectional study was conducted using clinical records...
- Letter to the Editor
- DOI: 10.1055/s-0045-1811731
- 3 Views
- 0 citations
- Published in
Phase-III INTERLACE Trial: A Study Requires Post-Hoc Analysis of Subgroups with Locally-Advanced Cervical Cancer
To the Editor, In recent years, few studies have provided oncological outcomes with the potential to change clinical practice for patients with cervical cancer, leaving the standard model of combined chemoradiotherapy for locally-advanced disease largely unchanged. Over the past year, 2 phase-III clinical trials—KEYNOTE-A181 and INTERLACE2—have introduced new evidence with...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1811626
- 4 Views
- 0 citations
- Published in
The action of Palbociclib on the Cell Cycle of Head and Neck Squamous Cell Carcinoma: A Systematic Review
Abstract This study evaluates the action of Palbociclib in the cell cycle of HPV-negative head and neck squamous cell carcinoma. Initially approved for HER2- and HR + breast cancer. Palbociclib induces cellular senescence, increases the efficacy of Cetuximab, restores p16 function and decreases phosphorylated Rb, suggesting an improvement in survival in both...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1809931
- 3 Views
- 0 citations
- Published in
Analysis of the Impact of the SARS-CoV-2 Pandemic on the Stage and Access to Oncology Services in Brazil for the Treatment of Rectal Cancer
Abstract Introduction Cancer is a major social, public health, and economic challenge worldwide, accounting for 1 in 6 deaths globally, according to Globocan 2022. Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there has been a noticeable impact on the provision of services to oncology patients. The present...
- Case Report
- DOI: 10.1055/s-0045-1811529
- 4 Views
- 0 citations
- Published in
Infrared Thermography – A Novel Tool in the Surgical Treatment of H3 K27M-Altered Diffuse Midline Spinal Cord Glioma: Technical and Case Report
Abstract Diffuse midline gliomas (DMGs), H3K27-altered, are rare and aggressive tumors primarily affecting children, though adult cases occur. These gliomas present significant surgical challenges, and novel techniques are needed to improve outcomes. We present the case of a 53-year-old male with a solid expansive lesion located at T12 to L1,...
- Original Article, Original Articles
- DOI: 10.1055/s-0045-1810447
- 4 Views
- 0 citations
- Published in
MultiClass Machine Learning-based Identification of Anoikis-related Genes Across Three Adult T-cell Leukemia/Lymphoma Subtypes
Abstract Introduction Adult T-cell leukemia/lymphoma (ATLL) is a type of cancer that originates from T-cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1). Anoikis is a programmed cell death process that occurs when the contact between cells or the extracellular matrix is lost. We aim to identify the...
- Case Report
- DOI: 10.1055/s-0045-1810445
- 3 Views
- 0 citations
- Published in
Papillary Carcinoma in a Thyroglossal Cyst: A Case Report
Abstract We herein report a case of papillary thyroid carcinoma with an unusual presentation, inside a thyroglossal cyst. An 83-year-old male patient reported a long-standing nodule persisting for over 40 years, with progressive enlargement and periodic dysphonia. The patient underwent total thyroidectomy combined with the Sistrunk procedure. Resection of the...
- Letter to the Editor
- DOI: 10.1055/s-0045-1809889
- 4 Views
- 0 citations
- Published in
Pharmacogenetic Testing for Fluoropyrimidines at Instituto Nacional de Câncer, Brazil
The present letter focuses on the pharmacogenetic (PGx) testing of variants of the dihydropyrimidine dehydrogenase (DPYD) gene available at Instituto Nacional de Câncer (INCA), Rio de Janeiro, for cancer patients who are candidates for treatment with the fluoropyrimidines 5-fluorouracil (5-FU) and/or capecitabine.1 The rationale for DPYD genotyping is as follows:...
2024 | XXV Congresso Brasileiro de Oncologia Clínica
Location: Rio de Janeiro, RJ, Brazil
Date: November 7, 2024
2022 | XXIII Congresso Brasileiro de Oncologia Clínica
Location: Windsor Convention & Expo Center
Date: November 3, 2022
2021 | III Semana Brasileira da Oncologia
Location: Centro de Convenções de Salvador
Date: November 17, 2021
2020 | SBOC – AACR Joint Congress: A Translational Approach to Clinical Oncology
Location: Virtual Meeting
Date: October 30, 2020
2019 | XXI Congresso da Sociedade Brasileira de Radioterapia (SBRT)
Location: Hotel Windsor Barra, in Rio de Janeiro (RJ)
Date: October 23, 2019
2019 | XXI Congresso Brasileiro de Oncologia Clínica (SBOC)
Location: Windsor Oceânico Hotel, Rio de Janeiro/RJ
Date: October 23, 2019