ABSTRACT Introduction: Pancreatic neoplasia is considered a serious disease, associated with high mortality rates and late diagnosis. This pathology corresponds in the Brazilian scenario, about 2% of the diagnosed cancers. The main risk factors are: advanced age, male sex, black race, smoking, obesity, diabetes, pancreatitis, excessive alcohol use, as well as...
ABSTRACT The inferior vena cava leiomyosarcoma is a rare type of retroperitoneal sarcoma. Due to the small number of cases reported in literature, there is no well-defined protocol, based on randomized studies, on the most appropriate treatment for this neoplasia. Studies show that surgical resection R0 is the main curative...
ABSTRACT Benefits of immunotherapy within modern oncology are evident, especially when evaluating survival, morbidity and systemic effects in the treatment of neoplastic tumors. However, adverse events have been described in association with checkpoint inhibitors. We aim to describe a case of bullous pemphigoid in a patient with metastatic melanoma treated...
ABSTRACT While lung carcinoma is the most common of the malignant tumors, primary lung tumors metastatic to the breast are rare and the prognosis is poor. We report a case of a Brazilian, 65- year-old, black, female patient with no family history of breast or lung cancer. During physical gynecological...
ABSTRACT A 64-year-old female patient with uncompensated fever and secretive cough, an active smoker with a history of tuberculosis treated irregularly, developed non-small cell lung cancer such as squamous cell carcinoma in the pulmonary cavernoma.
ABSTRACT The diagnosis of cervical mass is a challenge due to the wide variety of benign and malignant etiologies. Extrapulmonary small cell carcinomas (EPSCC) are rare entities, and those tumours arising as a primary cervical, especially in the thyroid gland, are exceedingly rare. As others small cell neuroendocrine carcinomas, the...
ABSTRACT We present a case of a 69 year-old, non-obese, post-menopausal woman diagnosed with synchronous endometrial adenocarcinoma and renal cell carcinoma. Immunolocalization and expression of the EGFR, HER-2, HER-3, HER-4 and p53 proteins by immunohistochemistry (IHC) was performed to investigate synchronous expression of these proteins. The endometrial adenocarcinoma was a...
ABSTRACT Applications for68 Ga-PSMA PET-CT continue to expand beyond prostate cancer. The objective of this case report is to illustrate a rare phenomenon known as tumor-totumor metastasis in which precise histological diagnosis is an essential prerequisite for correct clinical management of patients. A 89-year-old man with prostate cancer underwent68 Ga-PSMA...
ABSTRACT Giant-cell tumor is a relatively rare neoplasia, benign but locally aggressive, that causes significant bone destruction with predilection for epiphyseal and metaphyseal regions of long bones and the spine. Definitive treatment is surgical, with complete tumoral resection followed by autograft, homograft, arthrodesis, unconventional endoprostheses or methylmethacrylate. In most cases,...
ABSTRACT Metastatic castration-resistant prostate cancer (mCRPC) is an extremely severe disease that relentlessly evolves to death. Over the past few years, we have seen significant improvements in the different types of treatments available, which have positively impacted several clinical outcomes, including higher survival rates and better quality of life. Since...
