Abstract Introduction Gastric cancer is the fifth most common neoplasm and the fourth leading cause of cancer-related death in the world. The present review aims to offer to the oncologic community the molecular characterization of gastric cancer, the therapeutic innovations and the perspectives for the systemic therapy for gastric cancer. Materials...
Abstract Objective To estimate the incidental radiation dose delivered to the testicles in three-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc therapy (VMAT) in rectal cancer patients and its impact on sexual activity using a quality-of-life questionnaire. Materials and Methods The present study included 40 male patients, aged between 25...
Abstract The present review explores the role and impact of second opinions in medical oncology, particularly considering the recent advancements in artificial intelligence (AI) and telemedicine. A comprehensive literature search was conducted, and data from various studies were analyzed, highlighting why patients seek a second opinion, the rates of disagreement...
Abstract Cancer remains a significant public health challenge in Brazil, with an estimated 704 thousand new cases annually. Clinical oncology, a pivotal specialty in cancer diagnosis and treatment, has evolved since its formal establishment in 1946. Recent recognition by the Brazilian Federal Board of Medicine solidified its status, culminating in...
Abstract Primary mediastinal large B-cell lymphoma (PMBL) is an uncommon and aggressive subtype of non-Hodgkin large B-cell lymphoma that affects patients in the third and fourth decades of life. The objective of the present report is to describe the case of a male patient admitted to the emergency room with...
Abstract Breast cancer is a life-threatening disease and has serious health implications. It is categorized based on receptors, including the estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2), which are the focus of the present research We analyzed gene expression from data obtained from a functional genomics...
Evaluation of Treatment and Recurrence-Free Survival in Patients with Early HER2-Positive Breast Cancer: Real-Life Data Comparing Public and Private Healthcare
Abstract Introduction The present study was designed to compare the treatment provided in private and public health care facilities for women positive for early breast cancer of the human epidermal growth factor receptor 2 (HER2) subtype, who received anti-HER2 therapy in neoadjuvant or adjuvant settings, with an evaluation of the recurrence-free...
Postchemotherapy Robot-Assisted Retroperitoneal Lymph Node Dissection for Metastatic Testicular Cancer: Initial Experience at a Brazilian Oncology Center
Abstract Introduction Testicular cancer is the most common neoplasm in men aged 20 to 40 years. Retroperitoneal lymph node dissection plays an essential role in the treatment of such patients. Conventional open surgery has a complication rate of 30 to 36%. Some case series have demonstrated that a robot-assisted technique presented...
Abstract Justification The importance of this study arises from the high incidence and mortality of cervical cancer (CC), and the need to evaluate the effectiveness of current treatments, such as pelvic exenteration, performed in cases of persistent or recurrent carcinoma. Objective To analyze the relationship between clinical and pathological factors and the...
Abstract The term giant melanoma was previously characterized as a significantly large melanoma, often exceeding 10 cm in diameter. The present case report presents our experience in managing a giant malignant melanoma in the deltoid region in a 79-year-old patient. Due to the size of the lesion, surgical resection with reconstruction...
