ABSTRACT Introduction: The objective of our study is to present the first Brazilian irreversible electroporation experience in the treatment of solid cancer. Material and Methods: A retrospective study with the first ten patients who underwent percutaneous or surgical IRE to treat solid cancer between March 2021 and May 2021. Preoperative data collection...
ABSTRACT Gemcitabine is a widely used drug in the treatment of diverse malignancies and its use has been approved by the US Food and Drug Administration. This drug has been associated with a rare adverse event, the Hemolytic Uremic Syndrome (HUS), characterized by acute kidney injury, microangiopathic hemolytic anemia, and...
Using chemotherapy against metastatic pancreatic neuroendocrine neoplasm: how aggressively do we treat it? Real world data from a Brazilian Cancer Center
ABSTRACT Introduction: Pancreatic neuroendocrine neoplasms (pNEN) have poor prognosis. Available treatment options are limited. We aimed to evaluate the clinical characteristics and outcomes in patients with pNEN undergoing systemic chemotherapy. Methods: Retrospective study of patients with metastatic pNEN diagnosed between January 2000 and April 2018 in A.C. Camargo Cancer Center. We evaluated...
ABSTRACT Solid pseudopapillary tumors (SPTs) of the pancreas are rare tumors with low potential for malignancy, uncertain lineage, and favorable prognosis in most cases. The SPT has an excellent prognosis, and the standard treatment is surgical resection. The agenesis of the dorsal pancreas (ADP) is an extremely rare type of...
ABSTRACT Long-term survival of pancreatic ductal adenocarcinoma after surgery is still rare. One of the main reasons for unresectability is the tumor invasion of the main vessels, such as the celiac axis, common hepatic artery and superior mesenteric artery. The optimal management of these patients is controversial. Despite the challenges...
ABSTRACT Objective: Systemic treatment of advanced pancreatic adenocarcinoma has resulted in increased survival of patients, but real-life data are scarce, particularly in developing countries. This study aims to analyze the survival of patients with locally advanced, unresectable, or metastatic pancreatic cancer and factors related to better survival. Methods: an analytical study with...
ABSTRACT Peripheral primitive neuroectodermal tumors (pPNETs) are part of the Ewing sarcoma family. A few more than 30 cases of pPNETs originating on the pancreas have been reported in the consulted literature. We report a locally advanced pancreatic pPNET, with the longest follow-up and survival in the consulted literature, considering...
ABSTRACT Introduction: Pancreatic neoplasia is considered a serious disease, associated with high mortality rates and late diagnosis. This pathology corresponds in the Brazilian scenario, about 2% of the diagnosed cancers. The main risk factors are: advanced age, male sex, black race, smoking, obesity, diabetes, pancreatitis, excessive alcohol use, as well as...
ABSTRACT In 2018, there were some important trials presented over multiple international meetings. The objective of this article is to summarize the most important and practice changing studies in gastrointestinal oncology this year. Some studies in gastroesophageal, pancreatic, colorectal and anal canal have been selected, including adjuvant therapy in pancreatic...
