ABSTRACT Objectives: To evaluate the economic impact of the new form of radiotherapy remuneration published by the Ministry of Health. Methods: We design a simulated group of seventy patients from a database of a public institution. We compare the remuneration from SUS old payment methodology (SOPM), with the new form entitled of...
Central nervous system metastases of lung adenocarcinoma harboring EGFR-activating mutations: survival results from a multidisciplinary approach, including EGFR-TKIs
ABSTRACT Objectives: Central nervous system (CNS) metastases are frequent in advanced lung adenocarcinomas harboring EGFR-activating mutations. However, the best treatment approach must be defined. We aimed to evaluate the effectiveness of a multidisciplinary approach for CNS metastases in patients previously untreated with EGFR tyrosine kinase inhibitors (EGFRTKIs). Methods: We performed a retrospective...
ABSTRACT Radiation therapy (RT) uses high doses of high energy X-rays to kill cancer cells. Fractionation and volume optimization were the main methods used to increase the dose given to the tumor and reduce the dose and side effects to the normal tissues (NT). Conventional RT works with dose rates...
ABSTRACT The inferior vena cava leiomyosarcoma is a rare type of retroperitoneal sarcoma. Due to the small number of cases reported in literature, there is no well-defined protocol, based on randomized studies, on the most appropriate treatment for this neoplasia. Studies show that surgical resection R0 is the main curative...
ABSTRACT Benefits of immunotherapy within modern oncology are evident, especially when evaluating survival, morbidity and systemic effects in the treatment of neoplastic tumors. However, adverse events have been described in association with checkpoint inhibitors. We aim to describe a case of bullous pemphigoid in a patient with metastatic melanoma treated...
ABSTRACT Objectives: Osimertinib is a third-generation EGFR inhibitor with activity against both sensitizing and resistance mutations. Following results of the phase III study, AURA3, which led to the approval of osimertinib worldwide, we have conducted ASTRIS with the aim of confirming the efficacy and safety of osimertinib. Methods: This is a phase...
ABSTRACT Objectives: to identify the occurrence of toxicity associated with chemotherapy and predictors factors of hospitalization, delayed treatment, abandonment, treatment suspension or death. Methods: 126 patients with cancer were in a prospective cohort study, conducted between July/2012 and january/2013, they were interviewed before treatment and after completion of the 1st, 2nd and...
ABSTRACT The current pandemic moment of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) has completely changed health services, with most services being directed to the treatment of affected patients. Even during this critical period, cancer patients need to be treated, as delayed treatment can compromise the chances of a cure....
ABSTRACT Concerned with the evolution of COVID-19 in Brazil and its impact on our health system and oncology surgical assistance, the authors performed a review and suggested strategies for approach based on current evidence.
ABSTRACT In December 2019, a novel coronavirus disease (COVID-19) emerged in Wuhan, a city in the Hubei, Province of China. It rapidly spread in an epidemic fashion throughout China, followed by rapid increasing number of cases in many countries throughout the world, including Brazil. It is expected that oncologic patients...
