Abstract Introduction Time between cancer diagnosis and the start of treatment is crucial for patient prognosis. In the Brazilian public health system, this interval varies significantly. Access to timely care is shaped by multiple interconnected factors, including service organization, diagnostic processes, and follow-up care. Social aspects, such as ethnicity, level...
Abstract Introduction Maintenance of quality of life (QoL) is an important endpoint in cancer patients. Several studies have demonstrated that chemotherapy in breast cancer patients is related to worsening QoL scores. Taxanes are widely used in breast cancer treatment, and premedication omission in weekly paclitaxel has been evaluated in clinical...
Abstract Introduction Lung cancer is the most lethal cancer in the world. In Brazil, it is the third most common in men and the fourth in women. In Sergipe, this disease was the leading cause of cancer deaths from 2014 to 2018. Objectives To evaluate the mortality trend due to...
Abstract Introduction Oncology therapy development has accelerated worldwide, with approvals based on safety and efficacy. This study compares approval timelines in Brazil, the United States, and Europe from 2010 to 2021, highlighting regulatory differences and their impact on patient access. In Brazil, after Brazilian Health Regulatory Agency (Agência Nacional de...
Abstract Introduction Clinical trials are essential for advancing cancer care, yet patient participation remains low, particularly in regions with limited awareness such as Brazil. Materials and Methods This cross-sectional survey was conducted between 2020 and 2022 at a single cancer center in São Paulo, Brazil. Adult cancer patients completed a...
Abstract Objective To evaluate the feasibility and effectiveness of implementing virtual molecular tumor boards (MTBs) through crowdsourcing molecular knowledge among Brazilian physicians to comprehensively discuss complex genomic information on cancer patients. Materials and Methods We established a virtual group on WhatsApp (Meta Platforms, Inc.) consisting of medical oncologists, radiation therapists,...
Radionuclide Therapy for Bone Pain in Cancer Patients in Brazil (2015–2023): A Comparative Analysis of Public and Private Health Systems in the Context of the COVID-19 Pandemic
Abstract Introduction Bone metastases are common in advanced cancer and often result in severe pain. Radionuclide therapy with Beta-emitting radiopharmaceuticals, such as samarium-153 and strontium-89, is a recognized option for palliative management. The coronavirus disease 2019 (COVID-19) pandemic disrupted oncology care worldwide, including access to nuclear medicine services in Brazil....
Multidimensional Assessment of the Impact of Li-Fraumeni Syndrome on Patients in Educational and Pedagogical Settings: From Molecular to Psychosocial Aspects*
Abstract Introduction Li-Fraumeni syndrome (LFS) is a rare hereditary cancer predisposition syndrome caused by mutations in the TP53 gene. It presents a clinical challenge due to its wide phenotypic variability and significant psychosocial implications for affected individuals and their families. Objective To improve the identification, management, and follow-up strategies for...
Abstract Diffuse large B-cell lymphoma is the most common and aggressive subtype of B-cell non-Hodgkin lymphoma, and its occurrence during pregnancy or the postpartum period is rare. Management in this setting is challenging, due to risks to the mother and infant. We herein report the case of a 37-year-old woman...
Abstract To assess the degree of spirituality and religiosity in patients with breast cancer and its relationship with treatment, the Spiritual/Religious Coping (SRCOPE) scale and World Health Organization's Quality of Life Instrument – Spirituality, Religion and Personal Beliefs Module (WHOQOL-SRPB) questionnaires were applied to 49 patients. For 91.9% of the...
