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Uterine carcinosarcoma with microsatellite instability - does immunotherapy modify the therapeutic scenario? A case report and literature review

ABSTRACT Carcinosarcomas were reclassified by World Health Organization as high-grade uterine carcinomas in 2014. Due to its rare histology, comprising only 5% of uterine carcinomas, there is a small representation of this tumor in studies that evaluate metastatic uterine carcinomas treatment. In 2022, the treatment of metastatic uterine carcinomas has...
BJO Oncology - Placeholder

Epithelial-mesenchymal transition in uterine carcinosarcoma from a dedifferentiated papillary serous carcinoma to a sarcoma: case report

ABSTRACT Carcinosarcomas are endometrial neoplasms with malignant epithelial and mesenchymal components. These are rare tumors, corresponding to <5% of uterine cancers. The average age at diagnosis is 65 years and the most characteristic symptom is transvaginal bleeding, common to other uterine tumors. The definitive diagnosis of the lesion is done...
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Chronic renal failure as initial presentation of pelvic hemangioendothelioma.

ABSTRACT Hemangioendothelioma is a rare vascular tumor whose etiology has not yet been defined. Currently, it is known to affect different sites, such as the abdominal-pelvic cavity. It is also known to present intermediate characteristics to hemangioma and angiosarcoma. In recent studies, 50-76% of patients are asymptomatic. Surgical treatment is...
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Morbimortality related to the treatment of the soft tissue sarcomas

ABSTRACT Objective: To characterize patients with soft tissue sarcoma in their demographic, clinical, histopathological and treatment aspects, treatment toxicity, and postoperative complications occurring within 30 days of the first surgery. Methods: A retrospective cohort study with clinical data collection and referring to the treatment of patients with soft tissue sarcomas, obtained through...
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Primitive neuroectodermal tumor in advanced age: case report

ABSTRACT Objectives: Primitive neuroectodermal tumors (PNETs) are aggressive neuroectodermal neoplasms and are originated from neuroectodermal tissues. They belong to a larger group of tumors known as Ewing tumors and are unusual in adult population. This case reports PNET in the oldest patient quoted in literature and established it as a differential...
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Therapeutic approach of a pancreatic Ewing Sarcoma/PNET: case report and literature review

ABSTRACT Peripheral primitive neuroectodermal tumors (pPNETs) are part of the Ewing sarcoma family. A few more than 30 cases of pPNETs originating on the pancreas have been reported in the consulted literature. We report a locally advanced pancreatic pPNET, with the longest follow-up and survival in the consulted literature, considering...