Abstract Mucosal melanomas generally arise from mucosal epithelium lining the respiratory, alimentary, and genitourinary tracts and usually carry worse prognosis than cutaneous melanomas. Anorectal melanomas account for 50% of gastrointestinal tract melanomas and 0.3 to 1% of all malignant melanomas. There are no specific treatment guidelines due to the scarcity...
To the Editor, In recent years, few studies have provided oncological outcomes with the potential to change clinical practice for patients with cervical cancer, leaving the standard model of combined chemoradiotherapy for locally-advanced disease largely unchanged. Over the past year, 2 phase-III clinical trials—KEYNOTE-A181 and INTERLACE2—have introduced new evidence with...
Prostate cancer (PCa) is the second most commonly diagnosed male malignancy in the Western world.1 Radical prostatectomy and radiotherapy (RT), in their various modalities, are currently recommended as definitive treatment options, alone or in combination, in men with organ-confined, locally advanced, and oligometastatic disease. The literature has shown that higher...
Abstract Introduction Even though largely used, external beam parametrial boost concurrent with brachytherapy for advanced cervical cancer is consensual and lacks prospective evidence. Objective To assess the impact of external beam parametrial boost on cancer control and toxicity. Materials and Methods The present research is a retrospective, single, institutional study of patients with...
Prostate Cancer Stereotactic Body Radiation Therapy with Image-guided Radiation Therapy (IGRT) Technique with Three-Dimensional Transperineal Ultrasound for IGRT Tracking of the Prostate
Abstract Introduction Ultrahypofractionated radical radiotherapy for prostate cancer, also known as stereotactic body radiation therapy (SBRT), is an unprecedented modality of prostate radiotherapy and is still used very sparsely in Brazil. The use of fiducial implants and spacers may make it even more difficult to implement prostate SBRT on a large...
Abstract Objective To estimate the incidental radiation dose delivered to the testicles in three-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc therapy (VMAT) in rectal cancer patients and its impact on sexual activity using a quality-of-life questionnaire. Materials and Methods The present study included 40 male patients, aged between 25...
Iatrogenic tension pneumocephalus complication of osteoradionecrosis in the treatment of nasopharyngeal carcinoma. A case report and critical literature review
ABSTRACT Nasopharyngeal carcinoma typically originates in the fossa of Rosenmüller within the mucosal epithelium directly underlying the lymphatic tissue, and commonly presents clinically with symptoms such as headache, dizziness, and rhinorrhea. In this case study, we describe a 61-year-old man diagnosed with nasopharyngeal carcinoma who underwent radiation therapy with a...
ABSTRACT A 67-year-old male patient with a massive left axillary metastasis from an occult primary tumor (OPT) treated by stereotactic ablative radiotherapy (SABR) is presented. The patient had no clinical response to the initial chemotherapy treatment. Then, a SABR with a single fraction of 16Gy was performed. After SABR, a...
ABSTRACT Objectives: To evaluate the economic impact of the new form of radiotherapy remuneration published by the Ministry of Health. Methods: We design a simulated group of seventy patients from a database of a public institution. We compare the remuneration from SUS old payment methodology (SOPM), with the new form entitled of...
ABSTRACT Radiation therapy (RT) uses high doses of high energy X-rays to kill cancer cells. Fractionation and volume optimization were the main methods used to increase the dose given to the tumor and reduce the dose and side effects to the normal tissues (NT). Conventional RT works with dose rates...
