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BJO Oncology - Placeholder

Immunohistochemistry and next-generation sequencing for NTRK fusion detection in differentiated thyroid cancer of children, adolescents and young adults

Hecht, Fabio ID
,
de Lima Beltrão, Fabyan Esberard ID
,
Rios, Leonardo Freitas Boaventura ID
,
Machado, Gabriel Jeferson Rodríguez ID
,
Telles, Ana Clara Oliveira Tosta ID
,
Ramos, Helton Estrela ID
,
de-Oliveira, Taíse Lima Cerqueira ID
,
da-Paz, Alexandre Rolim ID
,
von-Ammon, Juliana Lima ID
,
da-Matta, Rafael Reis Campos ID
,
de Castro Lopes, Guilherme ID
,
Lisboa, Bruno da Silva ID
ABSTRACT Introduction: Pan-TRK immunohistochemistry staining can assess the protein expression from NTRK gene fusions. A little is known about its utility in differentiated thyroid cancer samples from children, adolescents, and young adults patients. Objective:Investigate pan-TRKimmunohistochemistry sensitivity and specificity in differentiated thyroid cancer samples from children, adolescents, and young adults patients....
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