Immunohistochemistry and next-generation sequencing for NTRK fusion detection in differentiated thyroid cancer of children, adolescents and young adults
ABSTRACT Introduction: Pan-TRK immunohistochemistry staining can assess the protein expression from NTRK gene fusions. A little is known about its utility in differentiated thyroid cancer samples from children, adolescents, and young adults patients. Objective:Investigate pan-TRKimmunohistochemistry sensitivity and specificity in differentiated thyroid cancer samples from children, adolescents, and young adults patients....
ABSTRACT Papillary carcinoma of the thyroglossal cyst is clinically like the benign lesion in adults aged 15-45 year, with a higher incidence in females. It is a congenital anomaly of the midline of the neck and have the clinical worsening related to infections of high aerodigestive routes. We discuss clinical...
