ABSTRACT A systematic review of published articles based on randomized clinical trials was conducted to ascertain the efficacy or perspective of using CAR-T cell therapy for refractory multiple myeloma. The PubMed database was searched with the combination of terms “multiple myeloma”, “refractory multiple myeloma”, “CAR T-cell”, and the PRISMA criteria...
ABSTRACT Introduction: Dermatofibrosarcoma (DFSP) is a rare neoplasia from mesenchymal tissues in the skin. It has a high potential for local invasion and a high rate of recurrence after the surgical excision. It appears as a hardened plaque of violaceous color, asymptomatic, which evolves with protuberant nodules. There are few Brazilian...
ABSTRACT Introduction: Chordoma is a malignant tumor that usually involves the axial skeleton. Intradural chordomas are even rarer and 37 cases have been reported to the best of our knowledge. We present a case of a patient with an atypical metastatic diffuse intradural spinal involvement. Objective: To investigate therapeutic approaches such as...
