ABSTRACT Urothelial carcinoma is a frequent worldwide malignancy. Poor survival rates in muscle-invasive and metastatic urothelial carcinoma impose major challenges for management. We conducted a consensus meeting to discuss the optimal treatment for urothelial carcinoma in Brazil, which was developed by a panel of multidisciplinary experts consisting of oncologists, urologists...
ABSTRACT Merkel cell carcinomas are rare cutaneous malignancies with neuroendocrine features that affect elderly individuals with a history of chronic sun exposure and immunosuppression. More recently, a human viral pathogen, the Merkel cell polyomavirus, has been implicated in the carcinogenesis of this disease. Its particularly aggressive biological behavior, the delay...
ABSTRACT NUT carcinoma (midline testicular carcinoma nuclear protein) is a relatively new, rare, aggressive and underdiagnosed entity. Its sites of involvement are medial structures of the head and neck and mediastinum, but other sites may be affected, and even in so-called common structures, the clinical course may impress. The objective...
ABSTRACT A 64-year-old female patient with uncompensated fever and secretive cough, an active smoker with a history of tuberculosis treated irregularly, developed non-small cell lung cancer such as squamous cell carcinoma in the pulmonary cavernoma.
ABSTRACT The diagnosis of cervical mass is a challenge due to the wide variety of benign and malignant etiologies. Extrapulmonary small cell carcinomas (EPSCC) are rare entities, and those tumours arising as a primary cervical, especially in the thyroid gland, are exceedingly rare. As others small cell neuroendocrine carcinomas, the...