ABSTRACT A 67-year-old male patient with a massive left axillary metastasis from an occult primary tumor (OPT) treated by stereotactic ablative radiotherapy (SABR) is presented. The patient had no clinical response to the initial chemotherapy treatment. Then, a SABR with a single fraction of 16Gy was performed. After SABR, a...
ABSTRACT Long-term survival of pancreatic ductal adenocarcinoma after surgery is still rare. One of the main reasons for unresectability is the tumor invasion of the main vessels, such as the celiac axis, common hepatic artery and superior mesenteric artery. The optimal management of these patients is controversial. Despite the challenges...
ABSTRACT Objective: To investigate the benefit of radiotherapy alone in patients diagnosed with locally advanced cervical cancer when the addition of chemotherapy was contraindicated. Methods: A single-center cohort study of patients diagnosed with locally advanced cervical cancer as defined by the FIGO 2009 (stage IB2 to IVA) and contraindication for concomitant chemotherapy...
ABSTRACT Introduction: Urothelial carcinoma, especially localized bladder cancer, has a substantial prevalence in Brazil with 9,480 new cases each year and 3,903 deaths, therefore progress is required in its management in order to decrease its recurrence and progression, and improve survival. Material and Methods: Medical oncologists, radiation oncologists, and urologists from Brazil...
ABSTRACT Solitary fibrous tumors of the pleura usually have a benign behavior, although some may present malignant characteristics - recurrences, metastases, and paraneoplastic syndromes. When a solitary fibrous tumor is responsible for the development of hypoglycemia, we have a case of Doege-Potter syndrome. We describe a case of a male...
ABSTRACT A pharmacogenetics/genomics (PGx) anticancer drug testing program is being developed by Kurtz and his group at the Brazilian National Cancer Institute (INCA). Drug -gene pairs were selected for PGx testing based on the presence of clinically validated PGx associations and the availability of international guidelines with PGx-informed dosing recommendations....
ABSTRACT Introduction: To evaluate whether the presence of bone metastasis in hospitalized patients with prostate cancer (PCa) is associated with a longer length of stay (LOS) when compared to LOS estimated by diagnosis-related groups (DRG). Methods: We performed a retrospective analysis of 86 admissions of patients with PCa at our facility in...
RESUMO Background: New antineoplastic agents have increased the survival rate of cancer patients, however, the incidence of cutaneous skin toxicity, which leads to worsening in the quality of life and to the necessity of interrupting the treatment, continues presently. Natural agents, as Aloe vera and Calendula, have been suggested as potential...
ABSTRACT Since the first report in Hubei, China, COVID-19 rapidly spread throughout the world and the World Health Organization (WHO) declared COVID-19 as global Pandemic on March 11, 2020. The first confirmed case in Brazil was on February 26, 2020. These outbreaks pose a greater threat to patients with cancer...
ABSTRACT Primary clear cell adenocarcinoma of the urethra is a rare malignancy and most of the cases described are in women. The symptomatology is similar to other tumors of the urethra. Because it is a rare malignancy and the consequent lack of trials in the medical literature, there is no...
