ABSTRACT Paraneoplastic vesiculobullous dermatomyositis is a rare disease characterized by proximal myopathy and typical cutaneus lesions which appear in a patient diagnosed with a malign neoplasia. In the present case, dermatomyositis developed four months after the detection of a breast carcinoma (T3N0M0) followed by radical mastectomy and lymph node dissection....
ABSTRACT The purpose of this systematic review (SR) was to identify interventions that are effective to prevent or reduce stress and burnout among oncologists. Search was conducted in eight electronic databases and grey literature databases, with no language or time restrictions. Included studies involved medical oncologists and contained interventions to...
ABSTRACT Introduction: The identification of innovative cancer biomarkers is a very relevant ongoing quest. Moreover, their role in cancer diagnosis and clinical management has been radically changed in the last few years with the major emphasis on cancer molecular classification, therapeutic target identification, and therapeutic protocol responsivity. tetraspanins are a family...
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is an extremely rare and potentially aggressive soft tissue tumor. Around 85 to 90% of DFSP cases are low-grade tumors, while the fibrosarcomatous variant (DFSP-FS) is associated with medium and high-grade neoplasms. DFSP affects more young adults, in their 30s; however, it can be present in...
ABSTRACT Objectives: This study aimed to characterize the clinical profile and the factors that predispose chemotherapy-induced nausea and vomiting (CINV) in the acute and delayed phases. Methods: A retrospective cohort study was conducted in a Brazilian hospital with pediatric patients under 18 years old receiving moderately or highly emetogenic chemotherapy. Thus, a...
ABSTRACT Introduction: Robotic nipple sparing mastectomy (RNSM) may be a breakthrough for breast cancer risk reduction surgeries, providing better aesthetic results. This study aims to spread the knowledge of the robotic surgical technique, still little performed in the world, and to demonstrate the applicability and surgical results. Methods: RNSM was offered to...
The addition of PD-1/PD-L1 axis blockade to BRAF and MEK inhibition for advanced melanoma patients harboring mutations: a systematic review and meta-analysis BRAF
ABSTRACT Objectives: Immune-checkpoint inhibitors (ICI) and targeted-therapies (TT) have become standard options for BRAF-V600 metastatic melanomas (MM). Recently, randomized trials (RCT) addressed the efficacy of combined approaches, with conflicting results. We sought to evaluate efficacy and safety of first-line combination ICI and BRAF/MEK inhibitors (triplets) versus BRAF/MEKi (doublets). Methods: We performed a...
ABSTRACT Introduction: The caregivers of cancer patients may experience changes in their routine that affect their quality of life. The aim of the study was to identify the domains that compromise the quality of life (QoL) of the caregivers of patients with gastrointestinal cancer (GIC). Methods: A descriptive, observational study with caregivers...
Clinical and sociodemographic profile of patients with cutaneous melanoma attended at an oncology referral hospital in Florianópolis between 2013 and 2017
ABSTRACT Introduction: Cutaneous melanoma is the most lethal skin cancer and its incidence has significantly increased in recent years. In particular, Florianópolis is the Brazilian capital with the highest incidence of the disease. Objective: To investigate the clinical and sociodemographic profile of patients with cutaneous melanoma treated at a public oncology referral...
ABSTRACT Introduction: Gallbladder cancer is a rare type of biliary tract malignancy with poorly defined pathogenesis, difficult treatment and often inoperable. Case Report: A 84-year-old male presented with pain in the right hypochondrium with three months of progressive worsening. Ultrasound routine examination showed the presence of a large mass in the gallbladder...
