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Spirituality in oncology - a consensus by the Brazilian Society of Clinical Oncology

ABSTRACT Spirituality is a dynamic and an intrinsic aspect of humanity and is usually intense in cancer for patients, families, and health care teams. Evidence on spirituality, health, and healing have increased over the last decades. This consensus is for those involved in cancer patient care, with concepts and possible...
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Is platelet-lymphocyte ratio (PLR) a predictor of thrombosis and together with circulating tumor cells capable to determine recurrence-free survival in patients with gastric cancer?

ABSTRACT Introduction: Cancer-associated thrombosis (CAT) is a major cause of morbidity and mortality in oncology patients. There are no accurate risk assessment tools to predict venous thromboembolism (VTE). Circulating tumor cells (CTCs), circulating tumor microemboli (CTM), and high platelet-lymphocyte ratio (PLR) may predispose to VTE. Objective: To evaluate correlations of CTCs, CTM,...
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Acute kidney injury in children with cancer admitted in an intensive care unit

ABSTRACT Objective: Evaluating the association between acute kidney injury and death in critically ill children with oncological diseases admitted in an intensive care unit (ICU). Material and Methods: Unicentric cohort study, evolving children with cancer admitted in the ICU of a pediatrics referral hospital. The patients were divided according to the presence...
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Knowledge of human papillomavirus vaccines among university students in Angola

ABSTRACT Introduction: Cervical cancer is the first most common cancer among women in Angola and accounts for 37.6% of cancers among women in Angola. The human papillomavirus (HPV) is a causative agent of the disease. Recent advances in technology have led to the introduction of vaccines to prevent HPV infection. This...
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The role of pelvic rehabilitation in quality of life in a patient harboring metastatic chordoma: a case report

ABSTRACT Introduction: Chordoma is a malignant tumor that usually involves the axial skeleton. Intradural chordomas are even rarer and 37 cases have been reported to the best of our knowledge. We present a case of a patient with an atypical metastatic diffuse intradural spinal involvement. Objective: To investigate therapeutic approaches such as...
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Evaluation of the impact of chemotherapy on eating habits of women with non-metastatic breast cancer

ABSTRACT Introduction: There are few studies that investigated the eating habits of patients with breast cancer undergoing chemotherapy. Objectives: To study the changes in dietary intake during chemotherapy, relating to sociodemographic variables, gastrointestinal side effects, and changes consumption in food groups. Material and Methods: This study was made at Clinical Oncology Department of...
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Analysis of trastuzumab therapy's efficacy with or without pertuzumab combination in the metastatic HER2-positive breast cancer an oncology hospital of Pernambuco

ABSTRACT Objectives: To evaluate the efficacy between trastuzumab-only or pertuzumab plus trastuzumab therapies in metastatic HER2-positive breast cancer patients. Material and Methods: At Hospital de Cancer de Pernambuco (HCP), Recife, Brazil, a cross-sectional study was carried out. One hundred seventy-two patients with HER2-positive metastatic breast cancer (BC) were divided into two groups....
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Incidental finding of sex cord tumor with annular tubules in ovary associated with Peutz-Jeghers syndrome

ABSTRACT Sex cord tumor with annular tubules (SCTAT) is a rare ovarian pathology. It is usually an incidental finding in asymptomatic patients. In about 30% of cases, this tumor is associated with the Peutz-Jeghers syndrome (PJS). This case report describes an incidental finding of SCTAT during an excisional surgery of...
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Protein carbonyl products, malondialdehyde, glutathione and vitamins C/E of breast cancer patients subjected to chemotherapy

ABSTRACT Introduction: Various endogenous and exogenous processes contribute to the production of oxidative stress, of which anticancer drugs may be one. This study aimed at evaluating the effect of breast cancer chemotherapy on oxidative stress. Material and Methods: Oxidative markers and antioxidant defense molecules were monitored in 59 women undergoing a year...
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Updated Brazilian guidelines for the management of immune-related adverse events associated with checkpoint inhibitors - edition 2.0

ABSTRACT Immunotherapy (IT) in the form of monoclonal antibodies targeting coreceptors involved in the modulation of the immune synapse represents a standard of care for patients with distinct malignancies. Over the past years, evidences supporting the clinical use of IT both in monotherapy, as well as in combinatorial regimens, grew...