ABSTRACT Objective: We sought to re-explore the association between well-known prognostic factors and recurrence in presumed early-stage low-risk endometrial cancer (EC). Methods: A retrospective cohort study was carried out on patients who underwent surgical treatment by the same surgeon for presumed early-stage low-risk EC between September 2003 to August 2017. The prognostic...
ABSTRACT Introduction: Treatment of locally advanced rectal cancer is based on chemoradiation associated with surgery. Tumor regression grade (TRG) appears to be a prognostic factor and be influenced by the interval between neoadjuvant treatment and surgery. Material and Methods: A retrospective database was formed. We included patients submitted to neoadjuvant chemoradiotherapy and...
ABSTRACT Objectives: This study aimed to determine the demographic and clinical profile of 1-to-5year head and neck cancer (HNC) survivors, and they oral features that could affect QoL. Material and Methods: In this cross-sectional study, medical records of 184 were reviewed concerning demographic, clinical and tumour characteristics. 40 of them underwent a...
ABSTRACT Objective: To describe the clinicopathological profile of breast cancer patients and association with excess body weight. Methods: This was a descriptive observational study of 126 women with breast cancer lesions treated between 2015 and 2017 at a cancer referral hospital for 27 municipalities in southwestern Paraná. Patients were categorized according to...
ABSTRACT Introduction: Older adults require attention to risks of treatment toxicity. The purpose of this study was to evaluate epidemiological data and clinical outcomes of patients with lung cancer treated with non-curative intent assessed by geriatric assessment (GA) and restricted access to new therapies. Methods: We evaluated older adults with non-small cell...
Analysis on complete pathological response and estimated survival among breast cancer patients undergoing neoadjuvant chemotherapy in a private institution in the state of Rio de Janeiro
ABSTRACT Objective: Breast cancer is the most common malignancy among women, both in developed and in developing countries. Indications for neoadjuvant treatment have been expanded so that pathological responses can be evaluated. Diversified therapeutic approaches may thus be indicated in accordance with each residual disease profile. This was a real-life study,...
ABSTRACT Introduction: Ovarian cancer (OC) is one of the leading causes of women's cancer deaths worldwide. Recent clinical trials with PARP inhibitors showed promising therapeutic opportunities for OC patients. The assessment of BRCA mutation is well established as relevant in the prevention, early diagnostic, and family counseling for OC, and recently...
ABSTRACT Objective: To investigate the benefit of radiotherapy alone in patients diagnosed with locally advanced cervical cancer when the addition of chemotherapy was contraindicated. Methods: A single-center cohort study of patients diagnosed with locally advanced cervical cancer as defined by the FIGO 2009 (stage IB2 to IVA) and contraindication for concomitant chemotherapy...
ABSTRACT Introduction: To evaluate whether the presence of bone metastasis in hospitalized patients with prostate cancer (PCa) is associated with a longer length of stay (LOS) when compared to LOS estimated by diagnosis-related groups (DRG). Methods: We performed a retrospective analysis of 86 admissions of patients with PCa at our facility in...
RESUMO Background: New antineoplastic agents have increased the survival rate of cancer patients, however, the incidence of cutaneous skin toxicity, which leads to worsening in the quality of life and to the necessity of interrupting the treatment, continues presently. Natural agents, as Aloe vera and Calendula, have been suggested as potential...
