Prostate cancer (PCa) is the second most commonly diagnosed male malignancy in the Western world.1 Radical prostatectomy and radiotherapy (RT), in their various modalities, are currently recommended as definitive treatment options, alone or in combination, in men with organ-confined, locally advanced, and oligometastatic disease. The literature has shown that higher...
Abstract The present study aimed to assess the sensitivity of the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) scale for scores other than 0 as a screening tool for sarcopenia in onco-hematology patients. A retrospective cohort study of 104 onco-hematology patients aged > 19 years and treated at the Diagnostic and Imaging...
Abstract Introduction Colorectal carcinoma is the result of a series of mutations based on the adenoma-carcinoma sequence. We aimed to perform a comparative analysis of the immune expression of the parkin (PARK2 gene) and of the APC (APC gene) proteins in samples of colorectal polyps and adenocarcinomas. Materials and Methods Through a...
Abstract Introduction Even though largely used, external beam parametrial boost concurrent with brachytherapy for advanced cervical cancer is consensual and lacks prospective evidence. Objective To assess the impact of external beam parametrial boost on cancer control and toxicity. Materials and Methods The present research is a retrospective, single, institutional study of patients with...
Abstract Metastatic cervical cancer presents new measures related to the association of biological therapies with conventional treatment that varies according to the presence of biomarkers. Based on a case report, we reviewed therapeutic modalities and updates on the use of concomitant immunobiological and oncological treatments to combat invasive cervical cancer....
Abstract Crizotinib is a multi-tyrosine kinase inhibitor (mTKI) with efficacy in treating c-ROS oncogene 1-positive non-small cell lung cancer (NSCLC). The association between this TKI and the development of renal cysts is well established, although data on the formation of aseptic abscesses is scarce. We report a case of a...
Abstract Introduction Cervical cancer remains a global health concern, particularly in low- and middle-income countries. Immunotherapy has demonstrated meaningful improvements in the overall survival (OS) of patients with recurrent, persistent, or metastatic disease that progressed to platinum-containing chemotherapy. The present study aimed to evaluate real-world outcomes with the use of immunotherapy...
Prostate Cancer Stereotactic Body Radiation Therapy with Image-guided Radiation Therapy (IGRT) Technique with Three-Dimensional Transperineal Ultrasound for IGRT Tracking of the Prostate
Abstract Introduction Ultrahypofractionated radical radiotherapy for prostate cancer, also known as stereotactic body radiation therapy (SBRT), is an unprecedented modality of prostate radiotherapy and is still used very sparsely in Brazil. The use of fiducial implants and spacers may make it even more difficult to implement prostate SBRT on a large...
Abstract Introduction The occurrence of errors in the prescription of antineoplastic oncological drugs constitutes a serious public health problem, directly affecting patient safety. In Brazil, the Protocol for the Safety in Prescription, Use, and Administration of Medications, established in 2013, aims to improve care related to medication use in healthcare facilities....
Abstract Introduction Sentinel lymph node biopsy (SLNB) has been proven to be a safe procedure in the treatment of endometrial cancer, and the instillment of a dye/marker in the cervix is the most used technique. Various studies have correlated the body mass index (BMI) impact as well as menopausal status and...
