ABSTRACT Objectives: To report real-world data of a cohort of patients treated with immune-checkpoint inhibitors in Brazil, with focus in immune-related adverse events. Material and Methods: In this retrospective study, we analyzed a cohort of patients with metastatic solid tumors treated at an oncology reference center with at least one dose of...
ABSTRACT Introduction: Gallbladder diseases are a well-studied subset of diseases in the Gangetic belt of India. But, the prevalence of gallbladder diseases, both benign and malignant (as a whole subset) has not been studied in Eastern Rajasthan yet. This study aims to provide an epidemiological overview of all histopathologically proven gall...
Lanolin-based dexpanthenol cream, topical hydrocortisone or observation in the prevention of capecitabine-induced hand-foot syndrome: a phase III trial
ABSTRACT Introduction: The use of capecitabine is associated with hand-foot syndrome (HFS). Since there is anecdotal evidence that lanolin-based creams and topical steroids are useful for the treatment of HFS, we conducted a three- arm phase III trial to compare observation, lanolin-based cream with dexpanthenol (L-D), and topical hydrocortisone in the...
ABSTRACT Objectives: To evaluate how hormonal therapy can impact breast cancer patients sexual quality of life and compare two widely used therapeutic agents: anastrozole and tamoxifen. Studies so far have evaluated the side effects of such therapy on patients general quality of life, but literature remains scarce regarding the impact it...
Subgroup analysis of Brazilian participants of a medical leadership competencies instrument: a cross-sectional survey study of the Latin American Cooperative Oncology Group (LACOG) and the Academy of Leadership Sciences Switzerland (ALSS)
ABSTRACT Introduction: We previously published the results of a medical leadership (ML) competencies instrument applied to Latin-American (LA) physicians with a leadership position, which disclosed meaningful differences in the valuation of specific ML competencies by LA physicians as compared to a similar survey applied to healthcare professionals from North America and...
ABSTRACT PRECONNECT is a multicenter study demonstrating the efficacy and tolerability of trifluridine/tipiracil in adult patients with histologically confirmed adenocarcinoma of the colon or rectum and pretreated metastatic lesions. The current article describes the characteristics and outcomes of the Brazilian cohort of patients who underwent trifluridine/tipiracil therapy within PRECONNECT. Brazilian...
ABSTRACT The aim of this integrative review was to identify scientific studies on risk factors for bloodstream infections associated with central venous catheters (CVC) in cancer patients. The research question was formulated according to the PICO framework. An electronic search was conducted on the SciELO digital library, the Virtual Health...
ABSTRACT Objectives: This study aims to identify prognostic factors and their discriminatory ability in inpatients with advanced cancer at a palliative care unit (PCU). Material and Methods: Observational, prospective cohort study involving advanced cancer patients (October 2019 to May 2021) of their first admission to a PCU. Sociodemographic, clinical, functional, nutritional, and...
ABSTRACT Objectives: The purpose of this study was to analyze the impact of COVID-19 on the use of blood components in an oncology hospital. Material and Methods: Retrospective cross-sectional quantitative nature cohort, with comparative analysis of blood component requests by an oncology hospital in the city of Juiz de Fora, Minas Gerais,...
ABSTRACT Introduction: The objective of our study is to present the first Brazilian irreversible electroporation experience in the treatment of solid cancer. Material and Methods: A retrospective study with the first ten patients who underwent percutaneous or surgical IRE to treat solid cancer between March 2021 and May 2021. Preoperative data collection...
