ABSTRACT Immunotherapy (IT) in the form of monoclonal antibodies targeting coreceptors involved in the modulation of the immune synapse represents a standard of care for patients with distinct malignancies. Over the past years, evidences supporting the clinical use of IT both in monotherapy, as well as in combinatorial regimens, grew...
ABSTRACT Radiation therapy (RT) uses high doses of high energy X-rays to kill cancer cells. Fractionation and volume optimization were the main methods used to increase the dose given to the tumor and reduce the dose and side effects to the normal tissues (NT). Conventional RT works with dose rates...
