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BJO Oncology - Placeholder

Ovarian cancer and BRCA mutation genetic testing: the Brazilian reality

ABSTRACT Introduction: Ovarian cancer (OC) is one of the leading causes of women's cancer deaths worldwide. Recent clinical trials with PARP inhibitors showed promising therapeutic opportunities for OC patients. The assessment of BRCA mutation is well established as relevant in the prevention, early diagnostic, and family counseling for OC, and recently...
BJO Oncology - Placeholder

COVID-19 and cancer: an extensive review

ABSTRACT Emerging data postulates that cancer is an important risk factor for disease severity and higher in-hospital mortality amongst patients with COVID-19. From a pathophysiological perspective, COVID-19 induces an overproduction of inflammatory cytokines, causing systemic inflammation, hypercoagulability, and multiple organ dysfunction syndrome. The exact pathophysiological mechanisms associated with severe COVID-19...
BJO Oncology - Placeholder

Physiotherapy in the context of palliative care in oncology: a pooled analysis

ABSTRACT Objective: To document the role of physiotherapy in the context of palliative care in cancer through an integrative literature review, as the prevalence and survival of cancer are increasing and physiotherapy can significantly contribute to the treatment of these patients. Methods: A search was made in the literature for scientific articles...
BJO Oncology - Placeholder

A spectacular tumor response of a giant axillary mass treated with SABR in a palliative scenario

ABSTRACT A 67-year-old male patient with a massive left axillary metastasis from an occult primary tumor (OPT) treated by stereotactic ablative radiotherapy (SABR) is presented. The patient had no clinical response to the initial chemotherapy treatment. Then, a SABR with a single fraction of 16Gy was performed. After SABR, a...