Using chemotherapy against metastatic pancreatic neuroendocrine neoplasm: how aggressively do we treat it? Real world data from a Brazilian Cancer Center
ABSTRACT Introduction: Pancreatic neuroendocrine neoplasms (pNEN) have poor prognosis. Available treatment options are limited. We aimed to evaluate the clinical characteristics and outcomes in patients with pNEN undergoing systemic chemotherapy. Methods: Retrospective study of patients with metastatic pNEN diagnosed between January 2000 and April 2018 in A.C. Camargo Cancer Center. We evaluated...
ABSTRACT The objective of this study was to identify the available evidence on the parameters that should be considered to improve the quality and safety of the prescription of systemic antineoplastic treatment. This is an integrative review carried out in the EMBASE, LILACS, and PubMed databases, from 2015 to 2019....
ABSTRACT Objective: We sought to re-explore the association between well-known prognostic factors and recurrence in presumed early-stage low-risk endometrial cancer (EC). Methods: A retrospective cohort study was carried out on patients who underwent surgical treatment by the same surgeon for presumed early-stage low-risk EC between September 2003 to August 2017. The prognostic...
ABSTRACT Introduction: Treatment of locally advanced rectal cancer is based on chemoradiation associated with surgery. Tumor regression grade (TRG) appears to be a prognostic factor and be influenced by the interval between neoadjuvant treatment and surgery. Material and Methods: A retrospective database was formed. We included patients submitted to neoadjuvant chemoradiotherapy and...
ABSTRACT Objective: This article describes the development process and summarizes the results of the Brazilian physical activity recommendations for cancer prevention and control, which was prepared to support health-care professionals. Material and Methods: These recommendations were elaborated considering: (i) the effect of physical activity on cancer prevention in the general healthy population;...
ABSTRACT Objectives: This study aimed to determine the demographic and clinical profile of 1-to-5year head and neck cancer (HNC) survivors, and they oral features that could affect QoL. Material and Methods: In this cross-sectional study, medical records of 184 were reviewed concerning demographic, clinical and tumour characteristics. 40 of them underwent a...
ABSTRACT Despite all advances in the treatment of neoplasms and substantial increases in fiveyear survival rates, most patients still die due to their diseases. Late diagnosis in some circumstances and resistance mechanisms throughout treatment still cause most patients to require palliative care integrated with cancer treatment, since diagnosis. Most palliative...
ABSTRACT Solid pseudopapillary tumors (SPTs) of the pancreas are rare tumors with low potential for malignancy, uncertain lineage, and favorable prognosis in most cases. The SPT has an excellent prognosis, and the standard treatment is surgical resection. The agenesis of the dorsal pancreas (ADP) is an extremely rare type of...
ABSTRACT Objective: To describe the clinicopathological profile of breast cancer patients and association with excess body weight. Methods: This was a descriptive observational study of 126 women with breast cancer lesions treated between 2015 and 2017 at a cancer referral hospital for 27 municipalities in southwestern Paraná. Patients were categorized according to...
ABSTRACT This report describes a rare case of malignant extraosseous giant cell tumor (GCT). It refers to a patient with an initial diagnosis of a locally advanced malignant GCT of the uterus, with disease progression to lung and mediastinum seven months after the diagnosis, requiring first line treatment with chemotherapy....
